abstract：:The purpose of this study was to establish the smallest dose of nasally administered salmon calcitonin (SCT) which, if given in conjunction with a previously published calcium/thiazide treatment, would be as effective as parenteral SCT in the treatment of Paget's disease of bone. Forty patients suffering from symptoma...

journal_title：Calcified tissue international

authors： Evans RA,Somers NM,Dunstan CR,Hills E,Evans M

更新日期：1991-09-01 00:00:00

abstract：:Ultrasonic methods measure properties intrinsic to bone's structure that are not necessarily dependent on bone mass. Therefore, ultrasound may prove to be a useful tool for diagnosing bone fragility and osteoporosis. The goal of this study was to determine the relationship between apparent velocity of ultrasound (AVU)...

journal_title：Calcified tissue international

authors： Turner CH,Eich M

更新日期：1991-08-01 00:00:00

abstract：:Hyperthyroidism and thyroid hormone substitutive therapy with serum iT3 in the normal range of values are known to lead to increased bone remodeling and loss of bone mass. We looked for a relationship between serum iT3 and bone metabolic or bone mass parameters in 402 euthyroid women aged 44-60. In a group of 93 preme...

journal_title：Calcified tissue international

authors： Schoutens A,Laurent E,Markowicz E,Lisart J,De Maertelaer V

更新日期：1991-08-01 00:00:00

abstract：:Tartrate resistant acid phosphatase (TRAP) has been proposed as a new biochemical marker for bone resorption. We have compared this new marker, TRAP, with the classical biochemical markers of bone remodelling, serum alkaline phosphatase (sAP), serum osteocalcin (sBGP), and with the urinary hydroxyproline/creatinine ra...

journal_title：Calcified tissue international

authors： Torres R,de la Piedra C,Rapado A

更新日期：1991-07-01 00:00:00

abstract：:Calcium and phosphate were allowed to diffuse into gelatin and Type I collagen gels which were then cut into slices and analyzed for ion concentrations. Solutions of calcium and phosphate were then prepared, with ion concentrations equivalent to the highest levels in the slices, and mixed together, whereupon a rapid a...

journal_title：Calcified tissue international

authors： Blumenthal NC,Cosma V,Gomes E

更新日期：1991-06-01 00:00:00

abstract：:Test implant plates surgically retrieved from distal femurs of dogs were studied by Raman spectroscopy in order to characterize the bone-implant interface. The implant surface consisted of phosphate mineral, plasma sprayed on a titanium substrate. On the basis of its spectroscopic signature, the phosphate mineral of b...

journal_title：Calcified tissue international

authors： Walters MA,Blumenthal NC,Leung Y,Wang Y,Ricci JL,Spivak JM

更新日期：1991-05-01 00:00:00

abstract：:The low interference with growth expected in child for a cortisol analogue, deflazacort (DFZ), prompted us to verify if DFZ could affect growth less than prednisone (PDN). An interim analysis relative to 27 girls and 38 boys (out of 100 expected) aged 3-12 yrs, after a median period of 14 mo.s is reported. Children wi...

journal_title：Calcified tissue international

authors： Aicardi G,Milani S,Imbimbo B,Vignolo M,Di Battista E,Gusmano R,Terragna A,Cordone G,Cottafava F,Coppo R

更新日期：1991-04-01 00:00:00

abstract：:1,25(OH)2D3 was found to regulate its own receptor levels via an increase in corresponding mRNA levels in human osteoblast-like osteosarcoma cells (MG-63). In addition, exposure of the cells for 24h to dexamethasone, estradiol, retinoic acid, or triiodothyronine resulted in a dose-dependent accumulation of hVDR mRNA. ...

journal_title：Calcified tissue international

authors： Mäenpää P,Mahonen A,Pirskanen A

更新日期：1991-01-01 00:00:00

abstract：:Cross-sectional and case-control studies are efficient and inexpensive approaches to the study of osteoporosis; their validity depends primarily on how the subjects are sampled. Retrospective studies of fractures may be biased if measurements change as a result of the fracture. Prospective cohort studies are less pron...

journal_title：Calcified tissue international

authors： Cummings SR

更新日期：1991-01-01 00:00:00

abstract：:The evidence now strongly supports a central role for oestrogen in the maintenance of the normal female skeleton. Loss of endogenous oestrogen leads to a period of accelerated bone loss which can be prevented with appropriate oestrogen replacement. The route of administration is not important provided adequate dosages...

journal_title：Calcified tissue international

authors： Hillard TC,Stevenson JC

更新日期：1991-01-01 00:00:00

abstract：:The effects of long-term running were studied in 20 beagle dogs. Ten dogs ran from the age of 15 weeks to the age of 70 weeks in a progressive program for up to 40 km/day. Ten sister dogs spent the same time in individual cages. At the age of 70 weeks the spines of the dogs were studied with regard to mineral density ...

journal_title：Calcified tissue international

authors： Puustjärvi K,Karjalainen P,Nieminen J,Helminen HJ,Soimakallio S,Kivimäki T,Arokoski J

更新日期：1991-01-01 00:00:00

abstract：:The mechanism whereby liposomal entrapment enhances the hypocalcemic effect of calcitonin (CT) was evaluated in the rat. Phosphatidylcholine (PC) and PC plus cholesterol (PCC) preparations of large multilammelar vesicles (MLV) and small unilammelar vesicles (SUV) were used to entrap human calcitonin (hCT). The effect ...

journal_title：Calcified tissue international

authors： Fukunaga M,Miller MM,Deftos LJ

更新日期：1990-12-01 00:00:00

abstract：:Energy-dispersive X-ray microanalysis was used to determine calcium/phosphorous (Ca/P) ratios in undecalcified teeth, and the sulfur (S) content of dentin of decalcified teeth from normal patients and patients with familial hypophosphatemia, in an attempt to determine the effect of phosphorus deficiency. The results s...

journal_title：Calcified tissue international

authors： Daley TD,Jarvis A,Wysocki GP,Kogon SL

更新日期：1990-12-01 00:00:00

abstract：:Cytochemical staining of normal human bone cells in monolayer cultures for alkaline phosphatase (ALP) indicated that the cultures contained mixed-cell populations. Time course evaluations of the cytochemical staining revealed, in addition to the ALP-negative cell population, at least two subpopulations of ALP-positive...

journal_title：Calcified tissue international

authors： Matsuyama T,Lau KH,Wergedal JE

更新日期：1990-11-01 00:00:00

abstract：:We have previously shown that cyclosporin A (CsA) produces high bone remodeling with resorption exceeding formation and loss of bone volume in the rat. This may have important clinical implications where CsA is widely used in organ transplantation. 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) is a bone mineralizing hormone ...

journal_title：Calcified tissue international

authors： Epstein S,Schlosberg M,Fallon M,Thomas S,Movsowitz C,Ismail F

更新日期：1990-09-01 00:00:00

abstract：:A strategy based on high pressure liquid chromatography (HPLC) techniques for the isolation or a principal amelogenin molecule from a single human dentition is described. A partial sequence (33 residues) for this 24 kDa amelogenin is presented and related to earlier studies of human 5 kDa tyrosine-rich amelogenin poly...

journal_title：Calcified tissue international

authors： Fincham AG,Hu YY,Lau E,Pavlova Z,Slavkin HC,Snead ML

更新日期：1990-08-01 00:00:00

abstract：:Monoclonal antibody against bovine serum alpha 2HS glycoprotein was raised in mice and the localization of this glycoprotein in bovine and human teeth was examined by immunohistochemical techniques on undemineralized ground sections after surface etching with dilute HCl. Positive reactions were found in both bovine an...

journal_title：Calcified tissue international

authors： Takagi Y,Shimokawa H,Suzuki M,Nagai H,Sasaki S

更新日期：1990-07-01 00:00:00

abstract：:The bone mineral density (BMD) of the radius and spine was determined by photo absorptiometry in a large number of controls (radius: n = 111; spine: n = 85; age range: 50-79 years) and osteoporotic women (radius: n = 98; spine n = 140; age range: 50-79 years) with at least one "atraumatic" vertebral compression fractu...

journal_title：Calcified tissue international

authors： Mautalen C,Vega E,Ghiringhelli G,Fromm G

更新日期：1990-04-01 00:00:00

abstract：:Bone resorption and formation in terms of milligram of calcium deposited into and released from whole humerus of 15-23 weeks old male rats were assessed, via linear least-squares regression analysis of change in calcium content and 3H-tetracycline kinetics of the bone. The rate of resorption was 0.376 mg calcium per d...

journal_title：Calcified tissue international

authors： Li XQ,Klein L

更新日期：1990-04-01 00:00:00

abstract：:The usefulness of various bone mineral measurement techniques is a subject of current controversy. In order to explore whether disparate conclusions may have arisen from differences in analytic methodology, data from published reports of bone mass and nonviolent fractures have been reanalyzed in terms of fracture risk...

journal_title：Calcified tissue international

authors： Ross PD,Davis JW,Vogel JM,Wasnich RD

更新日期：1990-03-01 00:00:00

abstract：:The present study was undertaken to determine the fluoride distribution profile in the rat femur. Male Wistar rats were divided into four groups and given water containing 0, 25, 50, and 100 ppm of fluoride, respectively, for 10 weeks. The fluoride distribution from the periosteum to the endosteum was determined in ea...

journal_title：Calcified tissue international

authors： Narita N,Kato K,Nakagaki H,Ohno N,Kameyama Y,Weatherell JA

更新日期：1990-03-01 00:00:00

abstract：:The absorption kinetics of intranasal salmon calcitonin were assessed in 4 normal subjects and 9 patients with Klinefelter's syndrome. After administration, absorption occurred within 5 minutes. There was a highly significant correlation between the amount administered and the amount absorbed (r = -0.83, P less than 0...

journal_title：Calcified tissue international

authors： Pun KK,Chan LW,Lau P,Ho PW,Wang C

更新日期：1990-02-01 00:00:00

abstract：:To investigate the effect of low doses of intranasal salmon calcitonin on plasma cyclic AMP (cAMP) and serum ionized calcium, 40 healthy postmenopausal women were randomized to receive a single dose of either placebo or 50, 100, or 200 IU of salmon calcitonin as a nasal spray. Blood samples were collected throughout a...

journal_title：Calcified tissue international

authors： Thamsborg G,Storm TL,Brinch E,Sykulski R,Fogh-Andersen N,Holmegaard SN,Sørensen OH

更新日期：1990-01-01 00:00:00

abstract：:In the rat, prolonged administration of the luteinizing, hormone-releasing hormone agonist buserelin (25 micrograms/kg body wt/day s.c.) lowers blood estradiol, raises bone resorption, and induces osteopenia. The present study was undertaken to determine whether withdrawal of buserelin normalizes blood estradiol, slow...

journal_title：Calcified tissue international

authors： Goulding A,Gold E

更新日期：1990-01-01 00:00:00

abstract：:N-acetyl-beta-D-glucosaminidase (NAG) is a lysosomal enzyme predominantly located in renal proximal tubules. In idiopathic hypoparathyroidism (IHP), 100 Units of human PTH (1-34) increased urinary excretion of NAG from 0.029 +/- 0.027 to 0.173 +/- 0.035 U/lGF (p less than 0.05) in two patients before treatment and fro...

journal_title：Calcified tissue international

authors： Mizunashi K,Furukawa Y,Taguchi K,Kuwahara M,Miura R,Yumita S,Yoshinaga K

更新日期：1989-12-01 00:00:00

abstract：:Osteoclastic bone resorption can be induced within the auditory bulla of the Mongolian gerbil by minute increases in air pressure. The objective of this study was to determine the rate at which osteoclasts are induced in areas of resorption and to compare the rate of osteoblast recruitment. Stainless steel tubes were ...

journal_title：Calcified tissue international

authors： Chole RA,Chan DE

更新日期：1989-11-01 00:00:00

abstract：:The extracellular protein matrix of developing enamel includes a major class of proteins, the amelogenins, which are believed to be concerned in regulating enamel biomineralization. Previous studies have shown the amelogenins of the extracellular matrix to be a complex of proline-rich hydrophobic proteins which, it is...

journal_title：Calcified tissue international

authors： Fincham AG,Hu YY,Pavlova Z,Slavkin HC,Snead ML

更新日期：1989-10-01 00:00:00

abstract：:We have used in situ hybridization to examine expression of collagen type I, II, and X mRNA and osteonectin mRNA in the chick epiphysis. Tissue samples from the proximal tibial growth cartilage were fixed in modified Carnoy's solution, dehydrated in ethanol, and embedded in paraffin. Longitudinal and transverse sectio...

journal_title：Calcified tissue international

authors： Oshima O,Leboy PS,McDonald SA,Tuan RS,Shapiro IM

更新日期：1989-09-01 00:00:00

abstract：:High resolution transmission electron microscopy (Hr TEM) studies on biological and synthetic calcium phosphate have provided information on the dissolution process at the crystal level. The purpose of this study was to investigate the dissolution of ceramic hydroxyapatite (HA) after implantation using Hr TEM. Recover...

journal_title：Calcified tissue international

authors： Daculsi G,LeGeros RZ,Mitre D

更新日期：1989-08-01 00:00:00

abstract：:Insulin is a potent stimulator of collagen synthesis and other osteoblastic cell functions. In various insulin-sensitive tissues, stimulation of glucose transport and glycolytic metabolism are hallmarks of insulin action and may play a role in insulin regulation of cellular function. However, the effects of insulin on...

journal_title：Calcified tissue international

authors： Ituarte EA,Halstead LR,Iida-Klein A,Ituarte HG,Hahn TJ

更新日期：1989-07-01 00:00:00

abstract：:We studied the epidemiology of osteoporotic fractures of the proximal femur (cervical and trochanteric fractures) in residents of Barcelona, aged 45 years or over, for a 1-year period. Fractures resulting from metastases were not included. During the period of observation, a total of 1,358 patients with hip fractures ...

journal_title：Calcified tissue international

authors： Diez A,Puig J,Martinez MT,Diez JL,Aubia J,Vivancos J

更新日期：1989-06-01 00:00:00

abstract：:In order to determine whether the bacterial bone resorbing agents lipopolysaccharide (LPS) and muramyl dipeptide (MDP) interact with osteoblasts, their effect on the synthesis of collagenase and tissue inhibitor or metalloproteinases (TIMP) from monolayer cultures of mouse osteoblast-like cells was investigated. All c...

journal_title：Calcified tissue international

authors： Sismey-Durrant HJ,Atkinson SJ,Hopps RM,Heath JK

更新日期：1989-05-01 00:00:00

abstract：:The purpose of this study was to investigate the mineral induction capacity in vitro of polyanionic proteins covalently bound to a surface. Rat dentin gamma-carboxyglutamate-containing protein of the osteocalcin type (Gla-protein), proteoglycan (PG), and phosphoprotein (PP-H), as well as phosvitin (PhV) and bovine ser...

journal_title：Calcified tissue international

authors： Linde A,Lussi A,Crenshaw MA

更新日期：1989-04-01 00:00:00

abstract：:Lumbar spine bone mass and density were measured with Dual photon absorptiometry (DPA) in 60 patients with crush fractures and 60 age-matched normal women. Short-term reproducibility of bone mineral density (BMD) was 1.3% in normal women and 2.5% in osteoporotic women; long-term reproducibility in normal women was 2.2...

journal_title：Calcified tissue international

authors： Pouilles JM,Tremollieres F,Louvet JP,Fournie B,Morlock G,Ribot C

更新日期：1988-12-01 00:00:00

abstract：:We investigated the ultrastructural distribution and histochemical properties of sulfated glycoconjugates, which could be preserved by glutaraldehyde fixation, in secretory ameloblasts and developing enamel matrix, by use of the high iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining and enzymatic...

journal_title：Calcified tissue international

authors： Kogaya Y,Furuhashi K

更新日期：1988-11-01 00:00:00

abstract：:The demonstration of histochemical characteristics in calcifying cartilage is fraught with methodological difficulties including the distinction of mineralized from unmineralized cartilage and the demonstration of cell detail in relatively hard tissue. This study uses the decalcified bone matrix-induced enchondral (en...

journal_title：Calcified tissue international

authors： Aaron RK,Jolly G,Ciombor DM,Barrach HJ

更新日期：1988-10-01 00:00:00

abstract：:To characterize osteopenic changes in ovariectomized (OVX) rats as a function of time, female Sprague Dawley rats (240 g body weight, 90 days old) were subjected to bilateral ovariectomy or sham surgery and killed at various times from 14-180 days postovariectomy. The proximal tibial metaphysis was processed undecalci...

journal_title：Calcified tissue international

authors： Wronski TJ,Cintrón M,Dann LM

更新日期：1988-09-01 00:00:00

abstract：:Prosected vertebrae and phalanges from 32 cadavera were examined using noninvasive methods commonly used for assessment of osteoporosis. Bone measures were then compared with a strength variable obtained by mechanically crushing or breaking the bones. All of the phalangeal density assessment techniques were found to b...

journal_title：Calcified tissue international

authors： Oyster N,Smith FW

更新日期：1988-08-01 00:00:00

abstract：:Plasma osteocalcin (BGP), growth hormone (GH), and somatomedin C(SmC) were measured in 12 patients with acromegaly [7 clinically active (aA), 5 cured (cA)] and 9 control subjects (C). Basal plasma values for the three parameters were higher in aA than in C and in cA. No significant difference was found between cA and ...

journal_title：Calcified tissue international

authors： de la Piedra C,Larrañaga J,Castro N,Horcajada C,Rapado A,Herrera Pombo JL,Carbó E

更新日期：1988-07-01 00:00:00

abstract：:Ectopic calcification of diseased tissues or around prosthetic implants can lead to serious disability. Therefore, calcification of implants of glutaraldehyde-cross-linked collagenous tissues and reconstituted collagen was compared with mineralization induced by demineralized bone matrix (DBM). Whereas implants of DBM...

journal_title：Calcified tissue international

authors： Nimni ME,Bernick S,Cheung DT,Ertl DC,Nishimoto SK,Paule WJ,Salka C,Strates BS

更新日期：1988-05-01 00:00:00